| 12/09/2021 | ELGOIBAR C.D. – MONDRAGON C.F. | 23/01/2022 |
| 19/09/2021 | MONDRAGON C.F. – AMAIKAK BAT K.E. | 30/01/2022 |
| 26/09/2021 | MUTRIKU F.T. – MONDRAGON C.F. | 06/02/2022 |
| 03/10/2021 | MONDRAGON C.F. – OIARTZUN K E | 13/02/2022 |
| 10/10/2021 | HERNANI C.D. – MONDRAGON C.F. | 20/02/2022 |
| 17/10/2021 | MONDRAGON C.F. – REAL UNION CLUB SAD | 27/02/2022 |
| 24/10/2021 | EUSKALDUNA S.D. – MONDRAGON C.F. | 06/03/2022 |
| 31/10/2021 | MONDRAGON C.F.- EIBAR S.A.D. | 13/03/2022 |
| 07/11/2021 |
ZARAUTZ K.E. – MONDRAGON C.F.
|
20/03/2022 |
| 14/11/2021 | MONDRAGON C.F. – ALOÑA MENDI K.E. | 27/03/2022 |
| 21/11/2021 | MONDRAGON C.F. – TOURING KE | 03/04/2022 |
| 28/11/2021 | UROLA K.E. – MONDRAGON C.F. | 10/04/2022 |
| 05/12/2021 | MONDRAGON C.F. – ALLERRU K.E. | 24/04/2022 |
| 12/12/2021 | ARETXABALETA K.E. UDA – MONDRAGON C.F. | 01/05/2022 |
| 19/12/2021 | MONDRAGON C.F. – BERGARA K.E. | 08/05/2022 |
| 09/01/2022 | ORDIZIA K.E. – MONDRAGON C.F. | 15/05/2022 |
| 16/01/2022 | MONDRAGON C.F. – AÑORGA K.K.E | 22/05/2022 |
